RESEARCH ARTICLE
Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer
Hornburg, Milena et al.
Highlights
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OXPHOS and IFN gene sets are enriched in infiltrated and excluded tumor cells.
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Pre-dysfunctional CD8+ GZMK T cells are enriched in excluded tumors.
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FCN1 monocytes and immature MARCO macrophages are enriched in desert tumors.
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CXCL16 is expressed primarily by infiltrated tumor cells and CXCR6 by T cells.
